DILIN Publications

Listed from most current to oldest articles.


DILIN Publications
DILIN0055 Vega M, Verma M, Beswick D, Bey S, Hossack J, Merriman N, Shah A, Navarro V, Drug Induced Liver Injury Network (DILIN). The Incidence of Drug- and Herbal and Dietary Supplement-Induced Liver Injury: Preliminary Findings from Gastroenterologist-Based Surveillance in the Population of the State of Delaware. Drug Saf. 2017 May 29. doi: 10.1007/s40264-017-0547-9. [Epub ahead of print]. PubMed PMID: 28555362. PubMed Central PMCID:


DILIN0054 Hayashi PH, Rockey DC, Fontana RJ, Tillmann HL, Kaplowitz N, Barnhart HX, Gu J, Chalasani NP, Reddy KR, Sherker AH, Hoofnagle JH; Drug-Induced Liver Injury Network (DILIN) Investigators. Death and liver transplantation within 2 years of onset of drug-induced liver injury. Hepatology. 2017 Oct;66(4):1275-1285. PubMed PMID: 28543844. PubMed Central PMCID: PMC5605419


DILIN0053 Chalasani N, Reddy KRK, Fontana RJ, Barnhart H, Gu J, Hayashi PH, Ahmad J, Stolz A, Navarro V, Hoofnagle JH. Idiosyncratic Drug Induced Liver Injury in African-Americans Is Associated With Greater Morbidity and Mortality Compared to Caucasians. Am J Gastroenterol. 2017 Sep;112(9):1382-1388. doi: 10.1038/ajg.2017.215. Epub 2017 Aug 1. PubMed PMID: 28762375. Central PMCID: NIHMS# 912080


DILIN0052 Urban TJ, Nicoletti P, Chalasani N, Serrano J, Stolz A, Daly A, Aithal G, Dillon J, Navarro V, Odin J, Barnhart H, Ostrov D, Long N, Cirulli ET, Watkins PB, Fontana RJ, on behalf of the Drug-Induced Liver Injury Network (DILIN), the Pharmacogenetics of Drug-Induced Liver Injury group (DILIGEN) and the International Serious Adverse Events Consortium (iSAEC). Minocycline Hepatotoxicity: Clinical characterization and identification of HLA-B* 35:02 as a risk factor. J Hepatol. 2017 Jul;67(1):137-144. doi: 10.1016/j.jhep.2017.03.010. [Epub ahead of print]. PubMed PMID: 28323125. PubMed Central PMCID: NIHMS# 871324


DILIN0051 Suzuki A, Barnhart H, Gu J, Bonkovsky HL, Tillmann HL, Fontana RJ, Kleiner DE, for Drug-induced Liver Injury Network (DILIN). Associations of gender and a proxy of female menopausal status with histological features of drug-induced liver injury. Liver International. 2017;1–8. doi: 10.1111/liv.13380. [Epub ahead of print] PubMed PMID: 28161910. Central PMCID: PMC5545077


DILIN0050 Navarro VJ, Khan I, Björnsson E, Seeff LB, Serrano J, and Hoofnagle JH. Liver Injury From Herbal and Dietary Supplements. Hepatology. 2017 Jan;65(1):363-373. doi: 10.1002/hep.28813. Epub 2016 Nov 17. PubMed PMID: 217981596; PubMed Central PMCID:PMC5502701


DILIN0049 Nicoletti P, Aithal GP, Bjornsson ES, Andrade RJ, Sawle A, Arrese M, Barnhart HX, Bondon-Guitton E, Hayashi PH, Bessone F, Carvajal A, Cascorbi I, Cirulli ET, Chalasani N, Conforti A, Coulthard SA, Daly MJ, Day CP, Dillon JF, Fontana RJ, Grove JI, Hallberg P, Hernández N, Ibáñez L, Kullak-Ublick GA, Laitinen T, Larrey D, Lucena MI, Maitland-van der Zee AH, Martin JH, Molokhia M, Pirmohamed M, Powell EE, Qin S, Serrano J, Stephens C, Stolz A, Wadelius M, Watkins PB, Floratos A, Shen Y, Nelson MR, Urban TJ, Daly AK; International Drug-Induced Liver Injury Consortium, Drug-Induced Liver Injury Network Investigators, and International Serious Adverse Events Consortium. Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study. Gastroenterology. 2017 Apr;152(5):1078-1089. doi: 10.1053/j.gastro.2016.12.016. [Epub ahead of print] PubMed PMID: 28043905. Central PMCID: PMC5367948


DILIN0048 Bonkovsky HL, Kleiner DE, Gu J, Odin JA, Russo MW, Navarro VM, Fontana RJ, Ghabril MS, Barnhart H, Hoofnagle JH, for the US Drug-Induced Liver Injury Network Investigators. Clinical presentations and outcomes of bile duct loss caused by drugs and herbals and dietary supplements. Hepatology 2017 Apr;65(4):1267-1277. Doi: 10.1002/hep.28967. [Epub ahead of print]. PubMed PMID: 217981596; PubMed Central PMCID: PMC5360519.


DILIN0047 Russo MW, Steuerwald N, Norton HJ, Anderson WE, Foureau D, Chalasani N, Fontana RJ, Watkins P, Serrano J, Bonkovsky HL. Profiles of miRNAs in Serum in Severe Acute Drug Induced Liver Injury and their Prognostic Significance. Liver Int. 2017 May;37(5):757-764. doi: 10.1111/liv.13312. [Epub ahead of print]. PubMed PMID: 27860186; PubMed Central PMCID: PMC5502673


DILIN0046 Whritenour J, Ko M, Zong Q, Wang J, Tartaro K, Schneider P, Olson E, VanVolkenburg M, Gu J, Serrano J, Hayashi P, Fontana R, Chalasani N, Bonkovsky HL. Development of a Modified Lymphocyte Transformation Test for Diagnosing Drug Induced Liver Injury Associated with an Adaptive Immune Response. Journal of Immunotoxicology, 2017; 14(1): 31-28. DOI: 10.1080/1547691X.2016.1254305. PubMed PMID: 28121193; PubMed Central PMCID: PMC5505862
DILIN0045 de Boer YS, Kosinski AS, Urban TJ, Zhao Z, Long N, Chalasani N, Kleiner DE, and Hoofnagle JH for the Drug-Induced Liver Injury Network. Features of Autoimmune Hepatitis in Patients with Drug-induced Liver Injury.  Clin Gastroenterol Hepatol. 2017 Jan;15(1):103-112. doi: 10.1016/j.cgh.2016.05.043. [Epub ahead of print] PubMed PMID: 27311619; PubMed Central PMCID: PMC5370577.


DILIN0044 Zheng EX, Rossi S, Fontana RJ, Vuppalanchi R, Hoofnagle JH, Khan I, and Navarro VJ for the Drug Induced Liver Injury Network (DILIN). Risk of Liver Injury Associated with Green Tea Extract in SLIMQUICK Weight Loss Products: Results from the DILIN Prospective Study. Drug Saf. 2016 Aug;39(8):749-54. doi: 10.1007/s40264-016-0428-7. PubMed PMID: 27189593; PubMed Central PMCID: PMC4961850.


DILIN0043 Heidemann LA, Navarro VJ, Ahmad, J, Hayashi PH, Stolz A, Kleiner DE, Fontana RJ on behalf of the DILIN Investigators. Severe Acute Hepatocellular Injury Attributed to OxyELITE Pro: A Case Series.    Dig Dis Sci. 2016 Sep;61(9):2741-8. doi: 10.1007/s10620-016-4181-7. Epub 2016 May 3. PubMed PMID: 27142670; PubMed Central PMCID: PMC4982804.


DILIN0042 Björnsson ES, Gu J, Kleiner DE, Chalasani N, Hayashi PH, Hoofnagle JH for the DILIN Investigators. Azathioprine and 6-Mercaptopurine Induced Liver Injury: Clinical Features and Outcomes. J Clin Gastroenterol. 2017 Jan;51(1):63-69. PubMed PMID: 27648552; PubMed Central PMCID:PMC5505863


DILIN0041 deLemos AS, Ghabril M, Rockey DC, Gu J, Barnhart HX, Fontana RJ, Kleiner DE, and Bonkovsky HL for the DILIN study investigators. Amoxicillin-Clavulanate Induced Liver Injury. Digestive Diseases and Sciences; Digestive Disease and Sciences 2016 Aug;61(8):2406-16. doi:10.​1007/​s10620-016-4121-6. PubMed PMID: 27003146; PubMed Central PMCID:PMC4945382


DILIN0040 Schmeltzer PA, Kosinski AS, Kleiner DE, Hoofnagle JH, Stolz A, Fontana RJ, Russo MW, MD for the Drug-Induced Liver Injury Network (DILIN). Liver Injury from Nonsteroidal Anti-inflammatory Drugs in the United States. Liver Int. 2016 Apr;36(4):603-9. doi: 10.1111/liv.13032. [Epub ahead of print]. PubMed PMID: 26601797; PubMed Central PMCID:PMC5035108


DILIN0039 Fontana RJ, Hayashi PH, Barnhart H, Kleiner DE, Reddy KR, Chalasani N, Lee WM, Stolz A, Phillips 3, Serrano J, Watkins PB and DILIN Investigators. Persistent Liver Biochemistry abnormalities are more common in older patients and those with Cholestatic Drug induced Liver Injury. Am J Gastroenterol 2015; 110:1450–1459; doi: 10.1038/ajg.2015.283. PubMed PMID:26346867; PubMed Central PMCID: PMC4784423.


DILIN0038 Usachov V, Urban TJ, Fontana RJ, Gross A, Lyer S, Omary MB, Strnad P. Prevalence of genetic variants of keratins 8 and 18 in patients with drug-induced liver injury. BMC Medicine (2015) 13:196 DOI 10.1186/s12916-015-0418-0. PubMed PMID:26286715; PubMed Central PMCID:PMC4545365


DILIN0037 Chalasani N, Bonkovsky HL, Fontana R, Lee W, Stolz A, Talwalkar J, Reddy KR, Watkins PB, Navarro V, Barnhart H, Gu J, Serrano J; United States Drug Induced Liver Injury Network. Features and Outcomes of 889 Patients with Drug-induced Liver Injury: The DILIN Prospective Study. Gastroenterology. 2015 Jun;148(7):1340-52. doi: 10.1053/j.gastro.2015.03.006. PubMed PMID: 25754159; PubMed Central PMCID:PMC4446235


DILIN0036 Hayashi PH, Fontana RJ, Chalasani NP, Stolz AA, Talwalker JA, Navarro VJ, Lee WM, Davern TJ, Kleiner DE, Gu J, Hoofnagle JH; U.S. DILIN Investigators. Under-reporting and Poor Adherence to Monitoring Guidelines for Severe Cases of Isoniazid Hepatotoxicity. Clin Gastroenterol Hepatol. 2015 Sep;13(9):1676-82. doi: 10.1016/j.cgh.2015.02.024. PubMed PMID: 25724701; PubMed Central PMCID: PMC4653068


DILIN0035 Alqahtani SA, Kleiner DE, Ghabril M, Gu J, Hoofnagle JH, Rockey DC; Drug-Induced Liver Injury Network Study Investigators. Identification and Characterization of Cefazolin-Induced Liver Injury. Clinical Gastroenterology and Hepatology, 2015 Jul;13(7):1328-1336. doi:10.1016/j.cgh.2014.11.036. PMID: 25528012; PubMed Central PMCID:PMC4472636


DILIN0034 Martinez MA, Vuppalanchi R, Fontana RJ, Stolz A, Kleiner DE, Hayashi PH, Gu J, Hoofnagle JH, Chalasani N. Clinical and histologic features of

azithromycin-induced liver injury. Clin Gastroenterol Hepatol 2015 Feb; 13(2): 369-376. PMID: 25111234; PubMed Central PMCID: PMC4321982.


DILIN0033 Vuppalanchi R, Navarro V, Vega M, Bonkovsky HL, Seeff L, Serrano J; Drug-Induced Liver Injury Network (DILIN). Herbal dietary supplement associated hepatotoxicity: an upcoming workshop and need for research. Gastroenterology. 2015 Mar;148(3):480-2. doi: 10.1053/j.gastro.2015.01.004. Epub 2015 Jan 8. PubMed PMID: 25579757;  PubMed Central PMCID: PMC4653067


DILIN0032 Bohm M, Vuppalanchi R, Chalasani N, and the Drug Induced Liver Injury Network (DILIN). Febuxostat-Induced Acute Liver Injury. Hepatology, 2016 Mar;63(3):1047-9. doi: 10.1002/hep.28403. Epub 2016 Feb 3. PubMed PMID: 26679098; PubMed Central PMCID: PMC4764455


DILIN0031 Foureau DM, Walling TL, Maddukuri V, Anderson W, Kleiner DE, Ahrens WA, Jacobs C, McKillop IH, Watkins P, Fontana RJ, Chalasani N, Talwalkar J, Lee WM, Reddy R, Stolz A, Serrano J and Bonkovsky HL. Comparative analysis of portal hepatic infiltrating leukocytes in acute drug-induced liver injury, idiopathic autoimmune and viral hepatitis. Clinical Experimental Immunology, 2015 Apr;180(1):40-51. doi: 10.1111/cei.12558. PubMed PMID:25418487; PubMed Central PMCID:PMC4367092


DILIN0030 Church RJ, Gatti DM, Urban TJ, Long N, Yang X, Shi Q, Eaddy JS, Mosedale M, Ballard S, Churchill GA, Navarro V, Watkins PB, Threadgill DW, Harrill AH. Sensitivity to Hepatotoxicity due to Epigallocatechin Gallate is Affected by Genetic Background in Diversity Outbred Mice. Food and Chemical Toxicology. 2015 Feb;76:19-26. doi: 10.1016/j.fct.2014.11.008. Epub 2014 Nov 28. PubMed PMID: 25446466; PubMed Central PMCID: PMC4324012.


DILIN0029 Navarro VJ, Barnhart H,   Bonkovsky HL, Davern T, Fontana RJ, Grant L, Reddy KR, Seeff LB, Serrano J, Sherker AH, Stolz A, Talwalkar J, Vega M, Vuppalanchi R. Liver Injury From Herbals and Dietary Supplements in the U.S. Drug-Induced Liver Injury Network. Hepatology. 2014; 60: 1399–1408. doi: 10.1002/hep.27317. PubMed PMID: 25043597; PubMed Central PMCID: PMC4293199


DILIN0028 Russo MW, Hoofnagle JH, Gu J, Fontana RJ, Barnhart H, Kleiner DE, Chalasani N, Bonkovsky HL. The spectrum of statin hepatotoxicity: Experience of the drug induced liver injury network. Hepatology. 2014 Aug;60(2):679-86. doi: 10.1002/hep.27157. PubMed PMID: 24700436; PubMed Central PMCID:PMC4110177


DILIN0027 Fontana RJ, Hayashi PH, Gu J, Reddy KR, Barnhart H, Watkins PB, Serrano J, Lee WM, Chalasani N, Stolz A, Davern T, Talwakar JA. Idiosyncratic Drug Induced Liver Injury is associated with Substantial Morbidity and Mortality within 6 months From Onset. Gastroenterology. 2014 Jul;147(1):96-108. pii: S0016-5085(14)00429-6. doi: 10.1053/j.gastro.2014.03.045. PubMed PMID: 24681128; PubMed Central PMCID: PMC4285559


DILIN0026 Hayashi PH, Barnhart HX, Fontana RJ, Chalasani N, Davern TJ, Talwalkar JA, Reddy KR, Stolz AA, Hoofnagle JH, Rockey DC. Reliability of Causality Assessment for Drug, Herbal and Dietary Supplement Hepatoxicity in the Drug-Induced Liver Injury Network (DILIN). Liver Int. 2015 May;35(5):1623-32. doi: 10.1111/liv.12540. PubMed PMID: 24661785; PubMed Central PMCID: PMC4305346


DILIN0025 Vuppalanchi R, Gotur R, Reddy KR, Fontana RJ, Ghabril M, Kosinski AS, Gu J, Serrano J, Chalasani N. Relationship Between Characteristics of Medications and Drug-Induced Liver Disease Phenotype and Outcome. Clinical Gastroenterology and Hepatology 2014 Sep;12(9):1550-5. doi: 10.1016/j.cgh.2013.12.016. PubMed PMID: 24362054; PubMed Central PMCID:PMC4065228




Steuerwald NM, Foureau DM, Norton HJ, Zhou J, Parsons JC, Chalasani N, Fontana RJ, Watkins PB, Lee WM, Reddy KR, Stolz A, Talwalkar J, Davern T, Saha D, Bell LN, Barnhart H, Gu J, Serrano J, Bonkovsky HL. Profiles of serum cytokines in acute drug-induced liver injury and their prognostic significance. PLoS One. 2013 Dec 27;8(12):e81974. doi: 10.1371/journal.pone.0081974. PubMed PMID: 24386086; PubMed Central PMCID:  PMC3873930.





Kleiner DE, Chalasani NP, Lee WM, Fontana RJ, Bonkovsky HL, Watkins PB, Hayashi PH, Davern TJ, Navarro V, Reddy R, Talwalkar JA, Stolz A, Gu J, Barnhart H, Hoofnagle JH; Drug-Induced Liver Injury Network (DILIN). Hepatic histological findings in suspected drug-induced liver injury: Systematic evaluation and clinical associations. Hepatology. 2014 Feb;59(2):661-70. doi: 10.1002/hep.26709. [Epub ahead of print] PubMed PMID: 24037963; PubMed Central PMCID: PMC3946736.


DILIN0022 Navarro VJ, Bonkovsky HL, Hwang SI, Vega M, Barnhart H, Serrano J. Catechins in dietary supplements and hepatotoxicity. Dig Dis Sci. 2013 Sep;58(9):2682-90. doi: 10.1007/s10620-013-2687-9. Epub 2013 Apr 27. PubMed PMID: 23625293; PubMed Central PMCID: PMC3769469.




Ghabril M, Bonkovsky HL, Kum C, Davern T, Hayashi PH, Kleiner DE, Serrano J, Rochon J, Fontana RJ, Bonacini M; US Drug-Induced Liver Injury Network. Liver injury from tumor necrosis factor-α antagonists: analysis of thirty-four cases. Clin Gastroenterology & Hepatology. 2013 May; 11(5):558-564.e3. Doi: 10.1016/j.cgh.2012.12.025. Epub 2013 Jan 17. PubMed PMID: 23333219; PubMed Central PMCID: PMC3865702.




Ghabril M, Fontana R, Rockey D, Jiezhun G, Chalasani N. Drug-induced liver injury caused by intravenously administered medications: the Drug-induced Liver Injury Network experience. J Clin Gastroenterol. 2013 Jul; 47(6):553-8. Doi: 10.1097/MCG.0b013e318276bf00. PubMed PMID: 23388845; PubMed Central PMCID: PMC3681898.




Fontana RJ, Hayashi P, Bonkovsky HL, Kleiner DE, Kochhar S, Gu J, Ghabril M. Presentation and outcomes with clinically apparent interferon beta hepatotoxicity. Dig Dis Sci. 2013 Jun; 58(6):1766-75. Doi: 10.1007/s10620-012-2553-1. Epub 2013 Feb 2. PubMed PMID: 23377559; PubMed Central PMCID: PMC3674196.




Grant LM, Kleiner DE, Conjeevaram HS, Vuppalanchi R, Lee WM. Clinical and histological features of idiosyncratic acute liver injury caused by temozolomide. Dig Dis Sci. 2013 May; 58(5):1415-21. doi: 10.1007/s10620-012-2493-9. Epub 2012 Dec 5. Review. PubMed PMID: 23212393. PubMed Central PMCID: PMC3826911





Urban TJ, Shen Y, Stolz A, Chalasani N, Fontana RJ, Rochon J, Ge D, Shianna KV, Daly AK, Lucena MI, Nelson MR, Molokhia M, Aithal GP, Floratos A, Pe’er I, Serrano J, Bonkovsky H, Davern TJ, Lee WM, Navarro VJ, Talwalkar JA, Goldstein DB, Watkins PB; Drug-Induced Liver Injury Network; DILIGEN; EUDRAGENE; Spanish DILI Registry; International Serious Adverse Events Consortium. Limited contribution of common genetic variants to risk for liver injury due to a variety of drugs. Pharmacogenet Genomics. 2012 Nov; 22(11):784-95. Doi: 10.1097/FPC.0b013e3283589a76. PubMed PMID: 22968431; PubMed Central PMCID: PMC3636716.




Urban TJ, Goldstein DB, Watkins PB. Genetic basis of susceptibility to drug-induced liver injury: what have we learned and where do we go from here? Pharmacogenomics. 2012 May; 13(7):735-8. Doi: 10.2217/pgs.12.45. PubMed PMID: 22594502; PubMed Central PMCID: PMC3641893.




Chalasani N, Vuppalanchi R, Navarro V, Fontana R, Bonkovsky H, Barnhart H, Kleiner DE, Hoofnagle JH. Acute liver injury due to flavocoxid (Limbrel), a medical food for osteoarthritis: a case series. Ann Intern Med. 2012 Jun 19; 156(12):857-60, W297-300. doi: 10.7326/0003-4819-156-12-201206190-00006. PubMed PMID: 22711078. PubMed Central PMCID: PMC3825458




Bell LN, Vuppalanchi R, Watkins PB, Bonkovsky HL, Serrano J, Fontana RJ, Wang M, Rochon J, Chalasani N; US Drug-Induced Liver Injury Network (DILIN) Research Group. Serum proteomic profiling in patients with drug-induced liver injury. Aliment Pharmacol Ther. 2012 Mar; 35(5):600-12. PubMed PMID: 22403816; PubMed Central PMCID: PMC3654532.




Davern TJ, Chalasani N, Fontana RJ, Hayashi PH, Protiva P, Kleiner DE, Engle RE, Nguyen H, Emerson SU, Purcell RH, Tillmann HL, Gu J, Serrano J, Hoofnagle JH; Drug-Induced Liver Injury Network (DILIN). Acute hepatitis E infection accounts for some cases of suspected drug-induced liver injury. Gastroenterology. 2011 Nov; 141(5):1665-72.e1-9. Doi: 10.1053/j.gastro.2011.07.051. Epub 2011 Aug 16. PubMed PMID: 21855518; PubMed Central PMCID: PMC3654540.




Molleston JP, Fontana RJ, Lopez MJ, Kleiner DE, Gu J, Chalasani N; Drug-Induced Liver Injury Network. Characteristics of idiosyncratic drug-induced liver injury in children: results from the DILIN prospective study. J Pediatr Gastroenterol Nutr. 2011 Aug; 53(2):182-9. Doi: 10.1097/MPG.0b013e31821d6cfd. PubMed PMID: 21788760; PubMed Central PMCID: PMC3634369.





Lucena MI, Molokhia M, Shen Y, Urban TJ, Aithal GP, Andrade RJ, Day CP, Ruiz-Cabello F, Donaldson PT, Stephens C, Pirmohamed M, Romero-Gomez M, Navarro JM, Fontana RJ, Miller M, Groome M, Bondon-Guitton E, Conforti A, Stricker BH, Carvajal A, Ibanez L, Yue QY, Eichelbaum M, Floratos A, Pe’er I, Daly MJ, Goldstein DB, Dillon JF, Nelson MR, Watkins PB, Daly AK; Spanish DILI Registry; EUDRAGENE; DILIN; DILIGEN; International SAEC. Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles. Gastroenterology. 2011 Jul; 141(1):338-47. doi: 10.1053/j.gastro.2011.04.001. Epub 2011 Apr 12. PubMed PMID: 21570397; PubMed Central PMCID:




Orman ES, Conjeevaram HS, Vuppalanchi R, Freston JW, Rochon J, Kleiner DE, Hayashi PH; DILIN Research Group. Clinical and histopathologic features of fluoroquinolone-induced liver injury. Clinical Gastroenterology & Hepatology. 2011 Jun; 9(6):517-523.e3. doi: 10.1016/j.cgh.2011.02.019. Epub 2011 Feb 26. PubMed PMID: 21356330; PubMed Central PMCID: PMC3718017.


DILIN0009 Vuppalanchi R, Hayashi PH, Chalasani N, Fontana RJ, Bonkovsky H, Saxena R, Kleiner D, Hoofnagle JH; Drug-Induced Liver Injury Network (DILIN). Duloxetine hepatotoxicity: a case-series from the drug-induced liver injury network. Aliment Pharmacol Ther. 2010 Nov; 32(9):1174-83. Doi: 10.1111/j.1365-2036.2010.04449.x. Epub 2010 Sep 3. PubMed PMID: 20815829. PubMed Central PMCID: PMC3773985




Fong TL, Klontz KC, Canas-Coto A, Casper SJ, Durazo FA, Davern TJ 2nd, Hayashi P, Lee WM, Seeff LB. Hepatotoxicity due to hydroxycut: a case series. Am J Gastroenterol. 2010 Jul; 105(7):1561-6. Doi: 10.1038/ajg.2010.5. Epub 2010 Jan 26. PubMed PMID: 20104221. PubMed Central PMCID: PMC3825455




Rockey DC, Seeff LB, Rochon J, Freston J, Chalasani N, Bonacini M, Fontana RJ, Hayashi PH; US Drug-Induced Liver Injury Network. Causality assessment in drug-induced liver injury using a structured expert opinion process: comparison to the Roussel-Uclaf causality assessment method. Hepatology. 2010 Jun; 51(6):2117-26. Doi: 10.1002/hep.23577. PubMed PMID: 20512999; PubMed Central PMCID: PMC3249230.




Agarwal VK, McHutchison JG, Hoofnagle JH; Drug-Induced Liver Injury Network. Important elements for the diagnosis of drug-induced liver injury. Clin Gastroenterol Hepatol. 2010 May; 8(5):463-70. Doi: 10.1016/j.cgh.2010.02.008. Epub 2010 Feb 17. Review. PubMed PMID: 20170750.  PMCID: PMC3901223




Fontana RJ, Seeff LB, Andrade RJ, Björnsson E, Day CP, Serrano J, Hoofnagle JH. Standardization of nomenclature and causality assessment in drug-induced liver injury: summary of a clinical research workshop. Hepatology. 2010 Aug; 52(2):730-42. Doi: 10.1002/hep.23696. PubMed PMID: 20564754; PubMed Central PMCID: PMC3616501.




Stewart JD, Horvath R, Baruffini E, Ferrero I, Bulst S, Watkins PB, Fontana RJ, Day CP, Chinnery PF. Polymerase γ gene POLG determines the risk of sodium valproate-induced liver toxicity. Hepatology. 2010 Nov; 52(5):1791-6. Doi: 10.1002/hep.23891. PubMed PMID: 21038416; PubMed Central PMCID:PMC3841971.




Fontana RJ, Watkins PB, Bonkovsky HL, Chalasani N, Davern T, Serrano J, Rochon J; DILIN Study Group. Drug-Induced Liver Injury Network (DILIN) prospective study: rationale, design and conduct. Drug Saf. 2009; 32(1):55-68. doi: 10.2165/00002018-200932010-00005. PubMed PMID: 19132805; PubMed Central PMCID: PMC3637941.




Chalasani N, Fontana RJ, Bonkovsky HL, Watkins PB, Davern T, Serrano J, Yang H, Rochon J; Drug Induced Liver Injury Network (DILIN). Causes, clinical features, and outcomes from a prospective study of drug-induced liver injury in the United States. Gastroenterology. 2008 Dec; 135(6):1924-34, 1934.e1-4. Doi: 10.1053/j.gastro.2008.09.011. Epub 2008 Sep 17. PubMed PMID: 18955056; PubMed Central PMCID: PMC3654244.




Rochon J, Protiva P, Seeff LB, Fontana RJ, Liangpunsakul S, Watkins PB, Davern T, McHutchison JG; Drug-Induced Liver Injury Network (DILIN). Reliability of the Roussel Uclaf Causality Assessment Method for assessing causality in drug-induced liver injury. Hepatology. 2008 Oct; 48(4):1175-83. Doi: 10.1002/hep.22442. PubMed PMID: 18798340; PubMed Central PMCID: PMC3618289.