DILIN Publications

Year Number  
2025 109 Halegoua-DeMarzio D, Stolz A, Avula B, Khan I, Navarro V. Meeting Report: Herbal and Dietary Supplement Safety Surveillance Summit. Drug Safety. 2025/08/09 2025;doi:10.1007/s40264-025-01589-8.  PMID:  40783601. PMCID:

 

2025 108 Rahnama-Moghadam S, Arora N, Vuppalanchi R, Li YJ, Gu J, Barnhart H, Phillips E, Chalasani N; Drug Induced Liver Injury Network. DRESS Syndrome in Patients With Drug-Induced Liver Injury: Characteristics and HLA Risk Factors.  Am J Gastroenterol. 2025 Jun 12. doi: 10.14309/ajg.0000000000003590. Online ahead of print. PMID: 40504263. PMCID:

 

2025 107 Vuppalanchi R, Li YJ, Rockey DC, Halegoua-DeMarzio D, Fontana RJ, Bonkovsky HL, Koh C, Odin J, Barnhart H, Hoofnagle JH; Drug‐Induced Liver Injury Network (DILIN). Clinical and Genetic Associations in Cephalosporin-Induced Liver Injury: Insights From the Drug-Induced Liver Injury Network. Aliment Pharmacol Ther. 2025 Jul 20. doi: 10.1111/apt.70284. Epub ahead of print. PMID: 40685563. PMCID:

 

2025 106 Ahmad J, Dellinger A, Nicoletti P, Barnhart HX, Ghabril M, Fontana RJ, Navarro V, Choi G, Hayashi PH, Gu J, Kleiner D; for the; Drug-Induced Liver Injury Network. Clinical and HLA Associations of Fluoroquinolone-Induced Liver Injury: Results From the Drug-Induced Liver Injury Network. Am J Gastroenterol. 2025 Apr 10:10.14309/ajg.0000000000003457. doi: 10.14309/ajg.0000000000003457. Epub ahead of print. PMID: 40207808; PMCID: PMC12353811 (available on 2026-04-10)

 

2025 105 Church RJ, Anchang B, Bennett BD, Bushel PR, Watkins PB. Blood Toxicogenomics Reveals Potential Biomarkers for Management of Idiosyncratic Drug-Induced Liver Injury. Front Genet. 2025.  16:1524433.

doi: 10.3389/fgene.2025.1524433. PMID: 40201567.  Free PMC article.

 

2025 104 Ahmad J, Li Y-J,  Phillips E, Dellinger A, Hayashi PH, Chalasani N, Fontana RJ, Kleiner DE, Barnhart HX, Hoofnagle JH.  Liver Injury due to Intravenous Methylprednisolone in the Drug-Induced Liver Injury Network.  Liver Int. 2025 Feb;45(2):e16242. doi: 10.1111/liv.16242. PMID: 39803998 PMCID: PMC11790010 (available on 2026-02-01)

 

2024 103 Gopalakrishna H, Ghabril M, Gu J, Li Y-J, Fontana R, Kleiner D, Koh C, Chalasani N. Drug-Induced Liver Injury due to Medications for Alcohol Use Disorder: Insights from the DILIN Prospective Study.  J Addict Med. 2024 Dec 9. doi: 10.1097/ADM.0000000000001421. Epub ahead of print. PMID: 39651750.  PMCID: PMC12133418

 

2024 102 Barritt AS, Hayashi PH, Stolz A, Barnhart H, Hoofnagle JH. Refinement of Hy’s Law using the Drug-Induced Liver Injury Network Database. Am J Gastroenterol.  2024 Oct 18. doi: 10.14309/ajg.0000000000003145. Online ahead of print.  PMID: 39422332.  PMCID: PMC12087471

 

2024 101 Chen V, Rockey D, Bjornsson E, Barnhart H, Hoofnagle JH. Incidence of Idiosyncratic Drug-Induced Liver Injury Caused by Prescription Drugs. Drug Safety.   2025 Feb;48(2):151-160. doi: 10.1007/s40264-024-01486-6. Epub 2024 Sep 24. PMID: 39317916 PMCID: PMC11785493 (available on 2026-02-01)

 

2024 100 Halegoua-DeMarzio D, Navarro V, Davis A, Ahmad J, Avula B, Barnhart H, Barritt S, Bonkovsky H, Chen V, Choi G, Fontana R, Ghabril M, Khan I, Koh C, Odin J, Rockey D, Rossi S, Rostami H, Serrano J, Sherker A, Stolz A, Tillmann H, Vuppalanchi R.  Investigation of the Role of Chemical Analysis in Causality Assessment of Herbal and Dietary Supplement-Induced Liver Injury. Drug Safety. 2025 Feb;48(2):143-150. doi: 10.1007/s40264-024-01484-8. Epub 2024 Oct 1.  PMID: 39354283 PMCID: PMC11785658

 

2024 99 Fontana RJ, Li YJ, Chen V, Kleiner D, Stolz A, Odin J, Vuppalanchi R, Gu J, Dara L, Barnhart H on behalf of the Drug Induced Liver Injury Network. Genetic Variants Associated with Immune Mediated Liver Injury from Checkpoint Inhibitors. Hepatology Communications.  2024 Aug 26;8(9):e0518. doi: 10.1097/HC9.0000000000000518.  PMID: 39185906 PMCID: PMC11357698

 

2024 98 Conlon C, Li Y-J, Ahmad J, Barnhart H,  Fontana RJ,  Ghabril M, Hayashi PH, Kleiner DE,  Lee WM, Navarro V, Odin J, Phillips EJ, Stolz A, Vuppalanchi R, Halegoua-DeMarzio D. Clinical Characteristics and HLA Associations of Azithromycin-Induced Liver Injury.  Aliment Pharmacol Ther. 2024 Sep;60(6):787-795. doi: 10.1111/apt.18160. Epub 2024 Jul 10. PMID: 38988034 PMCID: PMC11587661

 

2024 97 Choi G, Ahmad J, Navarro V, Thung S, Khan I, Avula B, Barnhart H, Stolz A. Characterization of an Outbreak of Acute Liver Injury After Ingestion of Plant Based Food Supplement. Aliment Pharmacol Ther., 2024 Aug;60(4):479-483. doi: 10.1111/apt.18116.   PMID: 38874448 PMCID: PMC11587764

 

2024 96 Masood U, Venturini N, Nicoletti P, Dellinger A, Kleiner D, Bonkovsky H, Barnhart H, Vuppalanchi R, Rossi S, Odin J, Kushner T. Clinical Features and Outcomes Associated With Drug-Induced Liver Injury in Pregnancy: The US Drug-Induced Liver Injury Network Experience.  Obstetrics & Gynecology,  Obstet Gynecol. 2024 Jun 1;143(6):819-823. doi: 10.1097/AOG.0000000000005585. Epub 2024 Apr 16. PMID: 38626448. PMCID: PMC11098677

 

2024 95 Bonkovsky HL, Ghabril M, Nicoletti P, Dellinger A, Fontana RJ, Barnhart H, Gu J, Daly AK, Aithal GP, Phillips EJ, Kleiner DE. Drug-Induced Liver Injury [DILI] ascribed to Non-steroidal Anti-inflammatory Drugs [NSAIDs] in the USA— Update with Genetic Correlations.  Liver Int. 2024 Mar 7. doi: 10.1111/liv.15892. Epub ahead of print. PMID: 38451034. PMCID:PMC12009671

 

2024 94 Pop A, Halegoua-DeMarzio D, Barnhart H, Kleiner D, Avigan M, Gu J, Chalasani N, Ahmad J, Fontana RJ, Lee W, Barritt AS. Amiodarone and Dronedarone Causes Liver Injury with Distinctly Different Clinical Presentations.  Dig Dis Sci. 2024 Feb 28. doi: 10.1007/s10620-023-08251-2. Epub ahead of print. PMID: 38416280. PMCID: 11026178.

 

2024 93 Fontana RJ. , Li Yi-Ju, Vuppalanchi R, Kleiner D, Gu J, Shroff Hersh M, Van W, Lisa B, Watkins P  on behalf of the US DILIN study group. ERAP-1 and ERAP-2 variants in Liver injury following COVID-19 mRNA Vaccination: A US Multicenter Study. The American Journal of Gastroenterology  2024 Aug 1;119(8):1496-1505.  PMID: 38314748 PMCID: PMC11296936

 

2024 92 Nicoletti P, Dellinger A, Li Y-J, Barnhart H, Phillips E, Chalasani N.  HLA-B*53:01 Is a Significant Risk Factor for Liver Injury Due to Phenytoin and Other Anti-epileptic Drugs in African Americans. The American Journal of Gastroenterology January 2024; 119(1):200-202; DOI: 10.14309/ajg.0000000000002454. PMID: 37552102. PMCID: PMC10841235

 

2023 91 Asif B, Koh C, Phillips EJ, Gu J, Li Y-J, Barnhart H, Chalasani N, Fontana RJ, Hayashi PH, Navarro VJ, Hoofnagle JH. Vancomycin Induced Liver Injury, DRESS, and HLA-A*32:01.   J Allergy Clin Immunol Pract. 2023 Sep 20:S2213-2198(23)01021-8. doi: 10.1016/j.jaip.2023.09.011. Epub ahead of print. PMID: 37739311.PMCID: PMC10885131

 

2023 90 Barritt AS 4th, Barnhart H, Gu J, Dellinger A, Rudnick S, Bonkovsky HL; DILIN Investigators. When Is Suspected Drug-Induced Liver Injury (DILI) Not DILI? An Analysis of Unlikely Cases From the Drug-Induced Liver Injury Network. Am J Gastroenterol.  2023 Dec 1;118(12):2301-2304. doi: 10.14309/ajg.0000000000002370. Epub ahead of print. PMID: 37311048. PMCID:10898250

 

2023 89 Fontana RJ, Kleiner DE, Chalasani N, Bonkovsky HL, Gu J, Barnhart H, Li YJ, Hoofnagle JH. The Impact of Patient Age and Corticosteroid Use in Patients With Sulfonamide Hepatotoxicity. Clin Gastroenterol Hepatol.  2023 Sep 1;118(9):1566-1575; DOI: 10.14309/ajg.0000000000002232.  PMID: 36848311.  PMCID: PMC10511659

 

2023 88 Nicoletti P, Dellinger A, Li YJ, Barnhart HX, Chalasani N, Fontana RJ, Odin JA, Serrano J, Stolz A, Etheridge AS, Innocenti F, Govaere O,  Grove JI, Stephens C, Aithal GP, Andrade RJ, Bjornsson ES, Daly AK, Lucena MI, Watkins P.  Identification of Reduced ERAP2 Expression and a Novel HLA Allele as Components of a Risk Score for Susceptibility to Liver Injury due to Amoxicillin-Clavulanate. Gastroenterology.   2023;164(3):454-466.  DOI: 10.1053/j.gastro.2022.11.036.  PMID: 36496055 PMCID: PMC9974860.

 

2023 87 Halegoua-DeMarzio D, Navarro V, Ahmad J, Avula B, Barnhart H, Barritt AS, Bonkovsky HL, Fontana RJ, Ghabril MS, Hoofnagle JH, Khan IA, Kleiner DE, Phillips E, Stolz A, Vuppalanchi R. Liver Injury Associated with Turmeric–a Growing Problem Ten Cases from the Drug-Induced Liver Injury Network [DILIN]. The American Journal of Medicine. 2023: 136(2): 200-206DOI: https://doi.org/10.1016/j.amjmed.2022.09.026.  PMID: 36252717.  PMCID: PMC9892270.

 

2023 86 Chalasani N, Li YJ, Dellinger A, Navarro V, Bonkovsky H, Fontana RJ, Gu J, Barnhart H, Phillips E, Lammert C, Schwantes-An TH, Nicoletti P, Kleiner DE, Hoofnagle JH; Drug Induced Liver Injury Network. Clinical features, outcomes, and HLA risk factors associated with nitrofurantoin-induced liver injury.  J Hepatol. 2023; 78(2):293-300. doi: 10.1016/j.jhep.2022.09.010. PMID: 36152763.  PMCID: PMC9852026.

 

2022 85 Ma J, Mathur K, Muldoon JL, Ghabril M, Chalasani N, Vuppalanchi R. Progressive Cholestasis and Biliary Cirrhosis After Initiating Oral Semaglutide: Report From the Drug-Induced Liver Injury Network. ACG Case Rep J. 2022 Dec 26;9(12):e00922. doi: 10.14309/crj.0000000000000922. PMID: 36600793; PMCID: PMC9794239.

 

2022 84 Fontana RJ, Engle RE, Hayashi PH, Gu J, Kleiner DE, Nguyen H, Barnhart H, Hoofnagle JH, Farci P.  The Incidence of Hepatitis E infection in American Patients with Suspected Drug-Induced Liver Injury Is Low and Declining: The DILIN Prospective Study. Am J Gastroenterol. 2022 Sep 1;117(9):1462-1470. PMID: 35973149 PMCID: PMC9437122

 

2022 83 Devarbhavi H, Ghabril M, Barnhart H, Patil M, Raj S, Gu J, Chalasani N, Bonkovsky HL. Leflunomide-Induced Liver Injury: Differences in Characteristics and Outcomes in Indian and US Registries. Liver International.   Liver Int. 2022 Jun;42(6):1323-1329. doi: 10.1111/liv.15189. PMID: 35129282 PMCID: PMC9187582

 

2022 82 Ahmad J, Barnhart HX, Bonacini M, Ghabril M, Hayashi PH,  Odin JA,  Rockey  DC, Rossi S, Serrano J, Tillmann HL, Kleiner DE. for the Drug-Induced Liver Injury Network. Value of liver biopsy in the diagnosis of drug-induced liver injury. Journal of Hepatology.   2022 May;76(5):1070-1078. https://doi.org/10.1016/j.jhep.2021.12.043. PMID: 35074471 PMCID: PMC9018618

 

2022 81 Hayashi PH, Lucena MI, Fontana RJ, Bjornsson ES, Aithal GP, Barnhart H, Gonzalez Jimenez A, Yang Q, Gu J, Andrade RJ, Hoofnagle JH. A Revised Electronic Version of RUCAM for the Diagnosis of Drug Induced Liver Injury. Hepatology. 2022 Jul; 76(1): 18–31. doi: 10.1002/hep.32327. PMID: 35014066.  PMCID: PMC9233102

 

2022 80 Chalasani N, Bonkovsky HL, Stine JG, Gu J, Barnhart H, Jacobsen E, Björnsson E, Fontana RJ, Kleiner DE, Hoofnagle JH; Drug-Induced Liver Injury Network (DILIN) Study Investigators. Clinical characteristics of antiepileptic-induced liver injury in patients from the DILIN prospective study. J Hepatol. 2022 Apr;76(4):832-840. doi: 10.1016/j.jhep.2021.12.013. PMID: 34953957 PMCID: PMCID8944173

 

2022 79 Vuppalanchi R, Bonkovsky HL, Ahmad J, Barnhart H, Durazo F, Fontana RJ, Gu J, Khan I, Kleiner DE, Koh C, Rockey DC, Phillips EJ, Li YJ, Serrano J, Stolz A, Tillmann HL, Seeff LB, Hoofnagle JH, Navarro VJ;  Garcinia cambogia, Either Alone or in Combination With Green Tea, Causes Moderate to Severe Liver Injury. Clin Gastroenterol Hepatol. 2022 Jun;20(6):e1416-e1425. doi: 10.1016/j.cgh.2021.08.015. PMID: 34400337 PMCID: PMC9004424

 

2021 78 Fontana RJ, Li YJ, Phillips E, Saeed N, Barnhart H, Kleiner D, Hoofnagle J on behalf of the Drug Induced Liver Injury Network. Allopurinol hepatotoxicity is associated with HLA Class I Alleles that vary by Ethnicity. Liver International, 2021; 41:1884-1893. doi: 10.1111/liv.14903. PMID: 33899326  PMCID:PMC8286350

 

2021 77 Ahmad J, Odin JA, Hayashi PH, Fontana RJ, Conjeevaram H, Avula B, Khan IA, Barnhart H, Vuppalanchi R, Navarro VJ; Drug-Induced Liver Injury Network. Liver injury associated with kratom, a popular opioid-like product: Experience from the U.S. drug induced liver injury network and a review of the literature. Drug Alcohol Depend. 2021 Jan 1;218:108426. doi: 10.1016/j.drugalcdep.2020.108426. PMID: 33257199. PMCID: PMC8113016

 

2021 76 Hoofnagle JH, Bonkovsky HL, Phillips EJ, Ahmad J, Barnhart H, Durazo F, Fontana RJ, Gu J, Khan I, Kleiner DE, Koh C, Li Y-J, Rockey DC, Seeff LB, Serrano J, Stolz A, Tillmann HL, Vuppalanchi R, Navarro VJ.  HLA-B*35:01 and Green Tea Induced Liver Injury. Hepatology. 2021 Jun;73(6):2484-2493. doi: 10.1002/hep.31538. PMID: 32892374 PMCID: PMC8052949

 

2021 75 Kim HP, Navarro V, Zacks S, Odin J, Kleiner DE, Hayashi PH. The Clinical Spectrum and Diagnosis of Oxaliplatin Liver Injury in the Era of Non-alcoholic Fatty Liver Disease.  Clin Gastroenterol Hepatol. 2021 Oct;19(10):2199-2201. doi: 10.1016/j.cgh.2020.09.038. PMID:  33007507 PMCID: PMC8007645.

 

2021 74 Li YJ, Phillips E, Dellinger A, Nicoletti P, Schutte R, Li, D, Ostrov DA, Fontana RJ, Watkins PB, Stolz A, Daly AK, Aithal GP, Barnhart H, Chalasani N. HLA‐B*14:01 and HLA‐B*35:01 are associated with trimethoprim‐sulfamethoxazole induced liver injury.  Hepatology. 2021 Jan;73(1):268-281. doi: 10.1002/hep.31258.  PMID: 32270503 PMCID: PMC7544638

 

2020 73 Lammert C, Zhu C, Lian Y, Ramani I, Eckert G, Li Q-Z, Chalasani N. An Exploratory Study of Autoantibody Profiling in Drug Induced Liver Injury with Autoimmune Phenotype. Hepatol Commun.   2020 Nov; 4(11): 1651–1663.  PMID:  33163835  PMCID: PMC7603536

 

2020 72 Ghabril M, Gu J, Yoder L, Corbito L, Dakhoul L, Ringel A, Beyer CD, Vuppalanchi R, Barnhart H, Hayashi PH, Chalasani N. Significant Medical Comorbidities Are Associated With Lower Causality Scores in Patients Presenting With Suspected Drug-Induced Liver Injury. Clin Transl Gastroenterol. 2020 Apr;11(4):e00141. doi: 10.14309/ctg.0000000000000141. PMID: 32251016  PMCID: PMC7263658

 

2020 71 Bjornsson HK, Bjornsson ES, Avula B, Khan IA, Jonasson JG, Ghabril M, Hayashi PH, Navarro V. Ashwagandha-induced liver injury: A case series from Iceland and the US Drug-Induced Liver Injury Network. Liver Int. 2020 Apr;40(4):825-829. doi: 10.1111/liv.14393. PMID:31991029 PMCID: PMC8041491

 

2019 70 Kamal N, Koh C, Samala N, Fontana R, Stolz A, Durazo F, Hayashi PH, Phillips E, Wang T, Hoofnagle JH.  Asparaginase-induced Hepatotoxicity: Rapid Development of Cholestasis and Hepatic Steatosis.  Hepatol Int. 2019 Sep;13(5):641-648. doi: 10.1007/s12072-019-09971-2. PMID: 31392570 PMCID: PMC7226930

 

2019 69 Ghabril M, Gu J, Yoder L, Corbito L, Ringel A, Beyer CD, Vuppalanchi R, Barnhart H, Hayashi PH, Chalasani N.  Development and Validation of Model Consisting of Comorbidity Burden to Calculate Risk of Death Within 6 months for Patients With Suspected Drug-Induced Liver Injury.  Gastroenterology.  2019 Nov; 157(5): 1245-1252. doi: 10.1053/j.gastro.2019.07.006. PMID: 31302142 PMCID:  PMC6815697

 

2019 68 Bonkovsky HL, Severson T, Nicoletti P, Barnhart H, Serrano J, Chalasani N, Fontana RJ, Watkins PB, Navarro V, Stolz A, Daly A, Aithal GP, Odin J. Genetic Polymorphisms Implicated in Nonalcoholic Liver Disease or Selected Other Disorders Have No Influence on Drug-Induced Liver Injury. Hepatol Commun. 2019 Jun 6;3(8):1032-1035. doi: 10.1002/hep4.1382.   PMID: 31388624 PMCID: PMC6671782

 

2019 67 Dipaola F, Molleston JP, Gu J, Cirulli ET, Chalasani N, Barnhart H, Kleiner DE, Hoofnagle JH, Fontana RJ, on behalf of the US Drug Induced Livery Injury Network. Antimicrobials and anti-epileptics are the leading causes of Idiosyncratic Drug Induced Liver Injury in Children. Journal of Pediatric Gastroenterology & Nutrition.  2019 Aug;69(2):152-159. doi: 10.1097/MPG.0000000000002383.   PMID: 31169665 PMCID: PMC6658343

 

2019 66 Stolz A, Navarro V, Hayashi PH, Fontana RJ, Barnhart HX, Gu J, Chalasani NP, Vega MM, Bonkovsky HL, Seeff LB, Serrano J, Avula B, Khan IA, Cirulli ET, Kleiner DE, Hoofnagle JH; DILIN Investigators. Severe and protracted cholestasis in 44 young men taking bodybuilding supplements: assessment of genetic, clinical and chemical risk factors. Aliment Pharmacol Ther. 2019 May;49(9):1195-1204. doi: 10.1111/apt.15211. PMID: 30934130 PMCID: PMC6682544

 

2019 65 Navarro V, Avula B, Khan I, Verma M, Seeff L, Serrano J, Fontana R, Ahmad J, Stolz A, for the Drug Induced Liver Injury Network Investigators. The Contents of Herbal and Dietary Supplements Implicated in Liver Injury in the United States are Frequently Mislabeled.  Hepatol Commun. 2019 Apr 3;3(6):792-794. doi: 10.1002/hep4.1346.  PMID: 31168513 PMCID: PMC6545864

 

2019 64 Ahmad, J., Reddy, KR, Tillmann, HL, Hayashi PH, Chalasani N, Fontana RJ, Navarro VJ, Stolz A, Barnhart H, Cloherty GA, Hoofnagle JH. Importance of Hepatitis C Virus RNA Testing in Patients with Suspected Drug-Induced Liver Injury.   Dig Dis Sci. 2019 Sep;64(9):2645-2652. doi: 10.1007/s10620-019-05591-w.  PMID: 30927209 PMCID: PMC6706305

 

2019 63 Cirulli ET, Nicoletti P, Abramson K, Andrade RJ, Bjornsson ES, Chalasani N, Fontana RJ, Hallberg P, Li YJ, Lucena MI, Long N, Molokhia M, Nelson MR, Odin JA, Pirmohamed M, Rafnar T, Serrano J, Stefansson K, Stolz A, Daly AK, Aithal GP, Watkins PB;  on behalf of Drug-Induced Liver Injury Network (DILIN) investigators and International DILI consortium (iDILIC). A Missense Variant in PTPN22 is a Risk Factor for Drug-induced Liver Injury.  Gastroenterology. 2019 May;156(6):1707-1716.e2. doi: 10.1053/j.gastro.2019.01.034.  PMID: 30664875 PMCID: PMC6511989

 

2019 62 Church RJ, Kullak-Ublick GA, Aubrecht J, Bonkovsky HL, Chalasani N, Fontana RJ, Goepfert JC, Hackman F, King NMP, Kirby S, Kirby P, Marcinak J, Ormarsdottir S, Schomaker SJ, Schuppe-Koistinen I, Wolenski F, Arber N, Merz M, Sauer JM, Andrade RJ, van Bömmel F, Poynard T, Watkins PB. Candidate biomarkers for the diagnosis and prognosis of drug-induced liver injury: An international collaborative effort. Hepatology. 2019 Feb;69(2):760-773. doi: 10.1002/hep.29802. PMID: 29357190; PubMed Central PMCID: PMC6054900.

 

2019 61 Ahmad J, Rossi S, Rodgers SK, Ghabril M, Fontana RJ, Stolz A, Hayashi PH, Barnhart H, Kleiner DE, Bjornsson ES. Sclerosing Cholangitis-Like Changes on Magnetic Resonance Cholangiography in Patients With Drug Induced Liver Injury.   Clin Gastroenterol Hepatol. 2019 Mar;17(4):789-790. doi: 10.1016/j.cgh.2018.06.035. PubMed PMID: 29966706. PubMed PMCID: PMC6311440.

 

2018 60 Bonkovsky H, Barnhart H, Foureau D, Steuerwald N, Lee W, Gu J, Fontana R, Hayashi P, Chalasani N, Navarro V, Odin J, Stolz A, Watkins P, Serrano J. Cytokine Profiles in Acute Liver Injury—Results from the US Drug-Induced Liver Injury Network (DILIN) and the Acute Liver Failure Study Group.   PLoS One. 2018 Oct 25;13(10):e0206389. doi: 10.1371/journal.pone.0206389. eCollection 2018. PubMed PMID: 30359443. PubMed PMCID: PMC6201986.

 

2018 59 Fontana RJ, Cirulli ET, Gu J, Kleiner D, Ostrov D, Phillips E, Schutte R, Barnhart H, Chalasani N, Watkins PB, Hoofnagle JH. The role of HLA-A*33:01 in patients with cholestatic hepatitis attributed to terbinafine. J Hepatol.  2018 Dec;69(6):1317-1325. doi: 10.1016/j.jhep.2018.08.004. PMID: 30138689 PMCID: PMC6472700

 

 

2018 58 Kowalec K, Wright GEB, Drögemöller B, Aminkeng F, Bhavsar AP, Kingwell E, Yoshida EM, Traboulsee A, Marrie RN, Kremenchutzky M, Campbell TL, Duquette P, Chalasani N, Wadelius M, Hallberg P, Xia Z, De Jager PL, Denny JC, Davis MF, Ross CJD, Tremlett H, and Carleton BC.   Common variation near IRF6 is associated with IFN-β-induced liver injury in multiple sclerosis; Nat Genet. 2018 Aug;50(8):1081-1085. doi: 10.1038/s41588-018-0168-y.  PMID: 30013178 PMCID: PMC6513312

 

2018 57 Dakhoul L, Ghabril M, Gu J, Navarro V, Chalasani N, Serrano J, for the United States Drug Induced Liver Injury Network.   Heavy Consumption of Alcohol is Not Associated With Worse Outcomes in Patients With Idiosyncratic Drug-induced Liver Injury Compared to Non-Drinkers. Clinical Gastroenterology and Hepatology, 2018; 16:722-729.  PubMed PMID: 29306044. PubMed Central PMCID: PMC5911195.

 

2017 56 Ahmad J, Odin JA, Hayashi PH, Chalasani N, Fontana RJ, Barnhart H, Cirulli ET, Kleiner DE, Hoofnagle JH. Identification and Characterization of Fenofibrate-Induced Liver Injury.  Dig Dis Sci. 2017; 62: 3596-3604. https://doi.org/10.1007/s10620-017-4812-7.   PubMed PMID: 29119413; PubMed PMCID: PMC5694705

 

2017 55 Vega M, Verma M, Beswick D, Bey S, Hossack J, Merriman N, Shah A, Navarro V, Drug Induced Liver Injury Network (DILIN).  The Incidence of Drug- and Herbal and Dietary Supplement-Induced Liver Injury: Preliminary Findings from Gastroenterologist-Based Surveillance in the Population of the State of Delaware.  Drug Saf (2017) 40: 783-787. doi: 10.1007/s40264-017-0547-9. PubMed PMID:  28555362.  PubMed Central PMCID:  PMC5699929

 

2017 54 Hayashi PH, Rockey DC, Fontana RJ, Tillmann HL, Kaplowitz N, Barnhart HX, Gu J, Chalasani NP, Reddy KR, Sherker AH, Hoofnagle JH; Drug-Induced Liver Injury Network (DILIN) Investigators.  Death and liver transplantation within 2 years of onset of drug-induced liver injury. Hepatology. 2017 Oct;66(4):1275-1285.  PubMed PMID: 28543844.  PubMed Central PMCID: PMC5605419

 

2017 53 Chalasani N, Reddy KRK, Fontana RJ, Barnhart H, Gu J, Hayashi PH, Ahmad J, Stolz A, Navarro V, Hoofnagle JH. Idiosyncratic Drug Induced Liver Injury in African-Americans Is Associated With Greater Morbidity and Mortality Compared to Caucasians. Am J Gastroenterol. 2017 Sep;112(9):1382-1388. doi: 10.1038/ajg.2017.215. PubMed PMID:  28762375.   Central PMCID: PMC5667647

 

2017 52 Urban TJ, Nicoletti P, Chalasani N, Serrano J, Stolz A, Daly A, Aithal G, Dillon J, Navarro V, Odin J, Barnhart H, Ostrov D, Long N, Cirulli ET, Watkins PB, Fontana RJ, on behalf of the Drug-Induced Liver Injury Network (DILIN), the Pharmacogenetics of Drug-Induced Liver Injury group (DILIGEN) and the International Serious Adverse Events Consortium (iSAEC). Minocycline Hepatotoxicity: Clinical characterization and identification of HLA-B* 35:02 as a risk factor.  J Hepatol. 2017 Jul;67(1):137-144. doi: 10.1016/j.jhep.2017.03.010. PubMed PMID: 28323125.  PubMed Central PMCID:  PMC5634615

 

2017 51 Suzuki A,  Barnhart H, Gu J, Bonkovsky HL, Tillmann HL, Fontana RJ,  Kleiner DE, for Drug-induced Liver Injury Network (DILIN).  Associations of gender and a proxy of female menopausal status with histological features of drug-induced liver injury. Liver International. 2017; 37(11):1723-1730. doi: 10.1111/liv.13380. PubMed PMID: 28161910.  Central PMCID:  PMC5545077

 

2017 50 Navarro VJ, Khan I, Björnsson E, Seeff LB, Serrano J, and Hoofnagle JH.  Liver Injury From Herbal and Dietary Supplements. Hepatology. 2017 Jan;65(1):363-373. doi: 10.1002/hep.28813. PubMed PMID: 217981596; PubMed Central PMCID:PMC5502701

 

2017 49 Nicoletti P, Aithal GP, Bjornsson ES, Andrade RJ, Sawle A, Arrese M, Barnhart HX, Bondon-Guitton E, Hayashi PH, Bessone F, Carvajal A, Cascorbi I, Cirulli ET, Chalasani N, Conforti A, Coulthard SA, Daly MJ, Day CP, Dillon JF, Fontana RJ, Grove JI, Hallberg P, Hernández N, Ibáñez L, Kullak-Ublick GA, Laitinen T, Larrey D, Lucena MI, Maitland-van der Zee AH, Martin JH, Molokhia M, Pirmohamed M, Powell EE, Qin S, Serrano J, Stephens C, Stolz A, Wadelius M, Watkins PB, Floratos A, Shen Y, Nelson MR, Urban TJ, Daly AK; International Drug-Induced Liver Injury Consortium, Drug-Induced Liver Injury Network Investigators, and International Serious Adverse Events Consortium. Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study. Gastroenterology. 2017 Apr;152(5):1078-1089. doi: 10.1053/j.gastro.2016.12.016. PubMed PMID: 28043905.  Central PMCID: PMC5367948

 

2017 48 Bonkovsky HL, Kleiner DE, Gu J, Odin JA, Russo MW, Navarro VM, Fontana RJ, Ghabril MS, Barnhart H, Hoofnagle JH, for the US Drug-Induced Liver Injury Network Investigators.  Clinical presentations and outcomes of bile duct loss caused by drugs and herbals and dietary supplements.  Hepatology 2017 Apr;65(4):1267-1277. Doi: 10.1002/hep.28967. PubMed PMID: 217981596; PubMed Central PMCID:  PMC5360519.

 

2017 47 Russo MW, Steuerwald N, Norton HJ, Anderson WE, Foureau D, Chalasani N, Fontana RJ, Watkins P, Serrano J, Bonkovsky HL. Profiles of miRNAs in Serum in Severe Acute Drug Induced Liver Injury and their Prognostic Significance. Liver Int. 2017 May;37(5):757-764. doi: 10.1111/liv.13312. PubMed PMID:  27860186; PubMed Central PMCID:  PMC5502673

 

2017 46 Whritenour J, Ko M, Zong Q, Wang J, Tartaro K, Schneider P, Olson E, VanVolkenburg M,  Gu J, Serrano J, Hayashi P, Fontana R, Chalasani N, Bonkovsky HL. Development of a Modified Lymphocyte Transformation Test for Diagnosing Drug Induced Liver Injury Associated with an Adaptive Immune Response. Journal of Immunotoxicology, 2017; 14(1): 31-28. DOI: 10.1080/1547691X.2016.1254305.  PubMed PMID: 28121193; PubMed Central PMCID: PMC5505862

 

2017 45 de Boer YS, Kosinski AS, Urban TJ,  Zhao Z, Long N, Chalasani N, Kleiner DE, and Hoofnagle JH  for the Drug-Induced Liver Injury Network. Features of Autoimmune Hepatitis in Patients with Drug-induced Liver Injury.   Clin Gastroenterol Hepatol. 2017 Jan;15(1):103-112. doi: 10.1016/j.cgh.2016.05.043. PubMed PMID: 27311619; PubMed Central PMCID: PMC5370577.

 

2017 44 Björnsson ES, Gu J, Kleiner DE, Chalasani N, Hayashi PH, Hoofnagle JH for the DILIN Investigators. Azathioprine and 6-Mercaptopurine Induced Liver Injury: Clinical Features and Outcomes.  J Clin Gastroenterol. 2017 Jan;51(1):63-69. PubMed PMID: 27648552; PubMed Central PMCID:PMC5505863

 

2016 43 Zheng EX, Rossi S, Fontana RJ,  Vuppalanchi R,  Hoofnagle JH,  Khan I, and Navarro VJ for the Drug Induced Liver Injury Network (DILIN). Risk of Liver Injury Associated with Green Tea Extract in SLIMQUICK Weight Loss Products: Results from the DILIN Prospective Study.  Drug Saf. 2016 Aug;39(8):749-54. doi: 10.1007/s40264-016-0428-7. PubMed PMID: 27189593; PubMed Central PMCID: PMC4961850.

 

2016 42 Heidemann LA, Navarro VJ, Ahmad, J, Hayashi PH, Stolz A, Kleiner DE,  Fontana RJ on behalf of the DILIN Investigators.  Severe Acute Hepatocellular Injury Attributed to OxyELITE Pro: A Case Series.    Dig Dis Sci. 2016 Sep;61(9):2741-8. doi: 10.1007/s10620-016-4181-7. PubMed PMID: 27142670; PubMed Central PMCID: PMC4982804.

 

2016 41 deLemos AS, Ghabril M, Rockey DC, Gu J, Barnhart HX,  Fontana RJ,  Kleiner DE, and Bonkovsky HL for the DILIN study investigators.  Amoxicillin-Clavulanate Induced Liver Injury. Digestive Diseases and Sciences; Digestive Disease and Sciences 2016 Aug;61(8):2406-16. doi:10.​1007/​s10620-016-4121-6. PubMed PMID: 27003146; PubMed Central PMCID:PMC4945382

 

2016 40 Schmeltzer PA, Kosinski AS, Kleiner DE, Hoofnagle JH, Stolz A, Fontana RJ, Russo MW, MD for the Drug-Induced Liver Injury Network (DILIN). Liver Injury from Nonsteroidal Anti-inflammatory Drugs in the United States.  Liver Int. 2016 Apr;36(4):603-9. doi: 10.1111/liv.13032. PubMed PMID:  26601797; PubMed Central PMCID:PMC5035108

 

2016 39 Bohm M, Vuppalanchi R, Chalasani N, and the Drug Induced Liver Injury Network (DILIN).  Febuxostat-Induced Acute Liver Injury. Hepatology, 2016 Mar;63(3):1047-9. doi: 10.1002/hep.28403. PubMed PMID: 26679098; PubMed Central PMCID:  PMC4764455

 

2015 38 Fontana RJ, Hayashi PH, Barnhart H, Kleiner DE, Reddy KR, Chalasani N, Lee WM, Stolz A, Phillips 3, Serrano J, Watkins PB and DILIN Investigators. Persistent Liver Biochemistry abnormalities are more common in older patients and those with Cholestatic Drug induced Liver Injury.   Am J Gastroenterol 2015; 110:1450–1459; doi: 10.1038/ajg.2015.283. PubMed PMID:26346867; PubMed Central PMCID: PMC4784423.

 

2015 37 Usachov V, Urban TJ, Fontana RJ, Gross A, Lyer S, Omary MB, Strnad P. Prevalence of genetic variants of keratins 8 and 18 in patients with drug-induced liver injury.  BMC Medicine (2015) 13:196 DOI 10.1186/s12916-015-0418-0. PubMed PMID:26286715; PubMed Central PMCID:PMC4545365

 

2015 36 Chalasani N, Bonkovsky HL, Fontana R, Lee W, Stolz A, Talwalkar J, Reddy KR, Watkins PB, Navarro V, Barnhart H, Gu J, Serrano J; United States Drug Induced Liver Injury Network. Features and Outcomes of 889 Patients with Drug-induced Liver Injury: The DILIN Prospective Study. Gastroenterology. 2015 Jun;148(7):1340-52. doi: 10.1053/j.gastro.2015.03.006. PubMed PMID: 25754159; PubMed Central PMCID:PMC4446235

 

2015 35 Hayashi PH, Fontana RJ, Chalasani NP, Stolz AA, Talwalker JA, Navarro VJ, Lee WM, Davern TJ, Kleiner DE, Gu J, Hoofnagle JH; U.S. DILIN Investigators. Under-reporting and Poor Adherence to Monitoring Guidelines for Severe Cases of Isoniazid Hepatotoxicity. Clin Gastroenterol Hepatol. 2015 Sep;13(9):1676-82. doi: 10.1016/j.cgh.2015.02.024. PubMed PMID: 25724701;  PubMed Central PMCID: PMC4653068

 

2015 34 Alqahtani SA, Kleiner DE, Ghabril M, Gu J, Hoofnagle JH, Rockey DC; Drug-Induced Liver Injury Network Study Investigators. Identification and Characterization of Cefazolin-Induced Liver Injury. Clinical Gastroenterology and Hepatology, 2015 Jul;13(7):1328-1336. doi:10.1016/j.cgh.2014.11.036.  PMID: 25528012; PubMed Central PMCID:PMC4472636

 

2015 33 Martinez MA, Vuppalanchi R, Fontana RJ, Stolz A, Kleiner DE, Hayashi PH, Gu J, Hoofnagle JH, Chalasani N. Clinical and histologic features of azithromycin-induced liver injury. Clin Gastroenterol Hepatol 2015 Feb; 13(2): 369-376. PMID: 25111234; PubMed Central PMCID: PMC4321982.

 

2015 32 Vuppalanchi R, Navarro V, Vega M, Bonkovsky HL, Seeff L, Serrano J; Drug-Induced Liver Injury Network (DILIN). Herbal dietary supplement associated hepatotoxicity: an upcoming workshop and need for research. Gastroenterology. 2015 Mar;148(3):480-2. doi: 10.1053/j.gastro.2015.01.004. PubMed PMID: 25579757;   PubMed Central PMCID: PMC4653067

 

2015 31 Foureau DM, Walling TL, Maddukuri V, Anderson W, Kleiner DE, Ahrens WA, Jacobs C, McKillop IH, Watkins P, Fontana RJ, Chalasani N, Talwalkar J, Lee WM, Reddy R, Stolz A, Serrano J and  Bonkovsky HL. Comparative analysis of portal hepatic infiltrating leukocytes in acute drug-induced liver injury, idiopathic autoimmune and viral hepatitis. Clinical Experimental Immunology, 2015 Apr;180(1):40-51.  doi: 10.1111/cei.12558. PubMed PMID:25418487; PubMed Central PMCID:PMC4367092

 

2015 30 Church RJ, Gatti DM, Urban TJ, Long N, Yang X, Shi Q, Eaddy JS, Mosedale M, Ballard S, Churchill GA, Navarro V,  Watkins PB, Threadgill DW, Harrill AH. Sensitivity to Hepatotoxicity due to Epigallocatechin Gallate is Affected by Genetic Background in Diversity Outbred Mice. Food and Chemical Toxicology. 2015 Feb;76:19-26. doi: 10.1016/j.fct.2014.11.008. PubMed PMID: 25446466; PubMed Central PMCID: PMC4324012.

 

2015 29 Hayashi PH, Barnhart HX, Fontana RJ, Chalasani N, Davern TJ, Talwalkar JA, Reddy KR, Stolz AA, Hoofnagle JH, Rockey DC.  Reliability of Causality Assessment for Drug, Herbal and Dietary Supplement Hepatoxicity in the Drug-Induced Liver Injury Network (DILIN).  Liver Int. 2015 May;35(5):1623-32. doi: 10.1111/liv.12540.  PubMed PMID: 24661785; PubMed Central  PMCID: PMC4305346

 

2014 28 Navarro VJ,  Barnhart H,  Bonkovsky HL,  Davern T, Fontana RJ, Grant L,  Reddy KR, Seeff LB, Serrano J, Sherker AH, Stolz A, Talwalkar J, Vega M, Vuppalanchi R. Liver Injury From Herbals and Dietary Supplements in the U.S. Drug-Induced Liver Injury Network. Hepatology. 2014; 60: 1399–1408. doi: 10.1002/hep.27317.  PubMed PMID: 25043597;  PubMed Central PMCID: PMC4293199

 

2014 27 Russo MW, Hoofnagle JH, Gu J, Fontana RJ, Barnhart H, Kleiner DE, Chalasani N, Bonkovsky HL.  The spectrum of statin hepatotoxicity: Experience of the drug induced liver injury network.  Hepatology. 2014 Aug;60(2):679-86. doi: 10.1002/hep.27157.  PubMed PMID: 24700436;  PubMed Central PMCID:PMC4110177

 

2014 26 Fontana RJ, Hayashi PH, Gu J, Reddy KR, Barnhart H, Watkins PB, Serrano J, Lee WM, Chalasani N, Stolz A, Davern T, Talwakar JA.  Idiosyncratic Drug Induced Liver Injury is associated with Substantial Morbidity and Mortality within 6 months From Onset.  Gastroenterology. 2014 Jul;147(1):96-108. pii: S0016-5085(14)00429-6. doi: 10.1053/j.gastro.2014.03.045. PubMed PMID: 24681128; PubMed Central  PMCID: PMC4285559

 

2014 25 Vuppalanchi R, Gotur R, Reddy KR, Fontana RJ, Ghabril M, Kosinski AS, Gu J, Serrano J, Chalasani N.  Relationship Between Characteristics of Medications and Drug-Induced Liver Disease Phenotype and Outcome. Clinical Gastroenterology and Hepatology 2014 Sep;12(9):1550-5. doi: 10.1016/j.cgh.2013.12.016.  PubMed PMID: 24362054; PubMed Central PMCID:PMC4065228

 

2014 24 Kleiner DE, Chalasani NP, Lee WM, Fontana RJ, Bonkovsky HL, Watkins PB, Hayashi PH, Davern TJ, Navarro V, Reddy R, Talwalkar JA, Stolz A, Gu J, Barnhart H, Hoofnagle JH; Drug-Induced Liver Injury Network (DILIN). Hepatic histological findings in suspected drug-induced liver injury: Systematic evaluation and clinical associations. Hepatology. 2014 Feb;59(2):661-70. doi: 10.1002/hep.26709. PubMed PMID: 24037963; PubMed Central PMCID: PMC3946736.

 

2013 23 Steuerwald NM, Foureau DM, Norton HJ, Zhou J, Parsons JC, Chalasani N, Fontana RJ, Watkins PB, Lee WM, Reddy KR, Stolz A, Talwalkar J, Davern T, Saha D, Bell LN, Barnhart H, Gu J, Serrano J, Bonkovsky HL. Profiles of serum cytokines in acute drug-induced liver injury and their prognostic significance. PLoS One. 2013 Dec 27;8(12):e81974. doi: 10.1371/journal.pone.0081974. PubMed PMID: 24386086; PubMed Central PMCID:  PMC3873930.

 

2013 22 Navarro VJ, Bonkovsky HL, Hwang SI, Vega M, Barnhart H, Serrano J. Catechins in dietary supplements and hepatotoxicity. Dig Dis Sci. 2013 Sep;58(9):2682-90. doi: 10.1007/s10620-013-2687-9. PubMed PMID: 23625293; PubMed Central PMCID: PMC3769469.

 

2013 21 Ghabril M, Bonkovsky HL, Kum C, Davern T, Hayashi PH, Kleiner DE, Serrano J, Rochon J, Fontana RJ, Bonacini M; US Drug-Induced Liver Injury Network. Liver injury from tumor necrosis factor-α antagonists: analysis of thirty-four cases. Clin Gastroenterology & Hepatology. 2013 May; 11(5):558-564.e3. Doi: 10.1016/j.cgh.2012.12.025. PubMed PMID: 23333219; PubMed Central PMCID: PMC3865702.

 

2013 20 Ghabril M, Fontana R, Rockey D, Jiezhun G, Chalasani N. Drug-induced liver injury caused by intravenously administered medications: the Drug-induced Liver Injury Network experience. J Clin Gastroenterol. 2013 Jul; 47(6):553-8. Doi: 10.1097/MCG.0b013e318276bf00. PubMed PMID: 23388845; PubMed Central PMCID: PMC3681898.

 

2013 19 Fontana RJ, Hayashi P, Bonkovsky HL, Kleiner DE, Kochhar S, Gu J, Ghabril M. Presentation and outcomes with clinically apparent interferon beta hepatotoxicity. Dig Dis Sci. 2013 Jun; 58(6):1766-75. Doi: 10.1007/s10620-012-2553-1. PubMed PMID: 23377559; PubMed Central PMCID: PMC3674196.

 

2013 18 Grant LM, Kleiner DE, Conjeevaram HS, Vuppalanchi R, Lee WM. Clinical and histological features of idiosyncratic acute liver injury caused by temozolomide. Dig Dis Sci. 2013 May; 58(5):1415-21. doi: 10.1007/s10620-012-2493-9. Review. PubMed PMID: 23212393. PubMed Central  PMCID: PMC3826911

 

2012 17 Urban TJ, Shen Y, Stolz A, Chalasani N, Fontana RJ, Rochon J, Ge D, Shianna KV, Daly AK, Lucena MI, Nelson MR, Molokhia M, Aithal GP, Floratos A, Pe’er I, Serrano J, Bonkovsky H, Davern TJ, Lee WM, Navarro VJ, Talwalkar JA, Goldstein DB, Watkins PB; Drug-Induced Liver Injury Network; DILIGEN; EUDRAGENE; Spanish DILI Registry; International Serious Adverse Events Consortium. Limited contribution of common genetic variants to risk for liver injury due to a variety of drugs. Pharmacogenet Genomics. 2012 Nov; 22(11):784-95. Doi: 10.1097/FPC.0b013e3283589a76. PubMed PMID: 22968431; PubMed Central PMCID: PMC3636716.

 

2012 16 Urban TJ, Goldstein DB, Watkins PB. Genetic basis of susceptibility to drug-induced liver injury: what have we learned and where do we go from here? Pharmacogenomics. 2012 May; 13(7):735-8. Doi: 10.2217/pgs.12.45. PubMed PMID: 22594502; PubMed Central PMCID: PMC3641893.

 

2012 15 Chalasani N, Vuppalanchi R, Navarro V, Fontana R, Bonkovsky H, Barnhart H, Kleiner DE, Hoofnagle JH. Acute liver injury due to flavocoxid (Limbrel), a medical food for osteoarthritis: a case series. Ann Intern Med. 2012 Jun 19; 156(12):857-60, W297-300. doi: 10.7326/0003-4819-156-12-201206190-00006. PubMed PMID: 22711078.  PubMed Central PMCID: PMC3825458

 

2012 14 Bell LN, Vuppalanchi R, Watkins PB, Bonkovsky HL, Serrano J, Fontana RJ, Wang M, Rochon J, Chalasani N; US Drug-Induced Liver Injury Network (DILIN) Research Group. Serum proteomic profiling in patients with drug-induced liver injury. Aliment Pharmacol Ther. 2012 Mar; 35(5):600-12. PubMed PMID: 22403816; PubMed Central PMCID: PMC3654532.

 

2011 13 Davern TJ, Chalasani N, Fontana RJ, Hayashi PH, Protiva P, Kleiner DE, Engle RE, Nguyen H, Emerson SU, Purcell RH, Tillmann HL, Gu J, Serrano J, Hoofnagle JH; Drug-Induced Liver Injury Network (DILIN). Acute hepatitis E infection accounts for some cases of suspected drug-induced liver injury. Gastroenterology. 2011 Nov; 141(5):1665-72.e1-9. Doi: 10.1053/j.gastro.2011.07.051. PubMed PMID: 21855518; PubMed Central PMCID: PMC3654540.

 

2011 12 Molleston JP, Fontana RJ, Lopez MJ, Kleiner DE, Gu J, Chalasani N; Drug-Induced Liver Injury Network. Characteristics of idiosyncratic drug-induced liver injury in children: results from the DILIN prospective study. J Pediatr Gastroenterol Nutr. 2011 Aug; 53(2):182-9. Doi: 10.1097/MPG.0b013e31821d6cfd. PubMed PMID: 21788760; PubMed Central PMCID: PMC3634369.

 

2011 11 Lucena MI, Molokhia M, Shen Y, Urban TJ, Aithal GP, Andrade RJ, Day CP, Ruiz-Cabello F, Donaldson PT, Stephens C, Pirmohamed M, Romero-Gomez M, Navarro JM, Fontana RJ, Miller M, Groome M, Bondon-Guitton E, Conforti A, Stricker BH, Carvajal A, Ibanez L, Yue QY, Eichelbaum M, Floratos A, Pe’er I, Daly MJ, Goldstein DB, Dillon JF, Nelson MR, Watkins PB, Daly AK; Spanish DILI Registry; EUDRAGENE; DILIN; DILIGEN; International SAEC. Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles. Gastroenterology. 2011 Jul; 141(1):338-47. doi: 10.1053/j.gastro.2011.04.001. PubMed PMID: 21570397; PubMed Central PMCID:

PMC3129430.

2011 10 Orman ES, Conjeevaram HS, Vuppalanchi R, Freston JW, Rochon J, Kleiner DE, Hayashi PH; DILIN Research Group. Clinical and histopathologic features of fluoroquinolone-induced liver injury. Clinical Gastroenterology & Hepatology. 2011 Jun; 9(6):517-523.e3. doi: 10.1016/j.cgh.2011.02.019. PubMed PMID: 21356330; PubMed Central PMCID: PMC3718017.

 

2010 9 Vuppalanchi R, Hayashi PH, Chalasani N, Fontana RJ, Bonkovsky H, Saxena R, Kleiner D, Hoofnagle JH; Drug-Induced Liver Injury Network (DILIN). Duloxetine hepatotoxicity: a case-series from the drug-induced liver injury network. Aliment Pharmacol Ther. 2010 Nov; 32(9):1174-83. Doi: 10.1111/j.1365-2036.2010.04449.x. PubMed PMID: 20815829. PubMed Central  PMCID: PMC3773985

 

2010 8 Fong TL, Klontz KC, Canas-Coto A, Casper SJ, Durazo FA, Davern TJ 2nd, Hayashi P, Lee WM, Seeff LB. Hepatotoxicity due to hydroxycut: a case series. Am J Gastroenterol. 2010 Jul; 105(7):1561-6. Doi: 10.1038/ajg.2010.5. PubMed PMID: 20104221. PubMed Central  PMCID: PMC3825455

 

2010 7 Rockey DC, Seeff LB, Rochon J, Freston J, Chalasani N, Bonacini M, Fontana RJ, Hayashi PH; US Drug-Induced Liver Injury Network. Causality assessment in drug-induced liver injury using a structured expert opinion process: comparison to the Roussel-Uclaf causality assessment method. Hepatology. 2010 Jun; 51(6):2117-26. Doi: 10.1002/hep.23577. PubMed PMID: 20512999; PubMed Central PMCID: PMC3249230.

 

2010 6 Agarwal VK, McHutchison JG, Hoofnagle JH; Drug-Induced Liver Injury Network. Important elements for the diagnosis of drug-induced liver injury. Clin Gastroenterol Hepatol. 2010 May; 8(5):463-70. Doi: 10.1016/j.cgh.2010.02.008. Review. PubMed PMID: 20170750.  PMCID: PMC3901223

 

2010 5 Fontana RJ, Seeff LB, Andrade RJ, Björnsson E, Day CP, Serrano J, Hoofnagle JH. Standardization of nomenclature and causality assessment in drug-induced liver injury: summary of a clinical research workshop. Hepatology. 2010 Aug; 52(2):730-42. Doi: 10.1002/hep.23696. PubMed PMID: 20564754; PubMed Central PMCID: PMC3616501.

 

2010 4 Stewart JD, Horvath R, Baruffini E, Ferrero I, Bulst S, Watkins PB, Fontana RJ, Day CP, Chinnery PF. Polymerase γ gene POLG determines the risk of sodium valproate-induced liver toxicity. Hepatology. 2010 Nov; 52(5):1791-6. Doi: 10.1002/hep.23891. PubMed PMID: 21038416; PubMed Central PMCID:PMC3841971.

 

2009 3 Fontana RJ, Watkins PB, Bonkovsky HL, Chalasani N, Davern T, Serrano J, Rochon J; DILIN Study Group. Drug-Induced Liver Injury Network (DILIN) prospective study: rationale, design and conduct. Drug Safety. 2009; 32(1):55-68. doi: 10.2165/00002018-200932010-00005. PubMed PMID: 19132805; PubMed Central PMCID: PMC3637941.

 

2008 2 Chalasani N, Fontana RJ, Bonkovsky HL, Watkins PB, Davern T, Serrano J, Yang H, Rochon J; Drug Induced Liver Injury Network (DILIN). Causes, clinical features, and outcomes from a prospective study of drug-induced liver injury in the United States. Gastroenterology. 2008 Dec; 135(6):1924-34, 1934.e1-4. Doi: 10.1053/j.gastro.2008.09.011. PubMed PMID: 18955056; PubMed Central PMCID: PMC3654244.

 

2008 1 Rochon J, Protiva P, Seeff LB, Fontana RJ, Liangpunsakul S, Watkins PB, Davern T, McHutchison JG; Drug-Induced Liver Injury Network (DILIN). Reliability of the Roussel Uclaf Causality Assessment Method for assessing causality in drug-induced liver injury. Hepatology. 2008 Oct; 48(4):1175-83. Doi: 10.1002/hep.22442. PubMed PMID: 18798340; PubMed Central PMCID: PMC3618289.